Publication: Effectiveness of home rehabilitation program for ischemic stroke upon disability and quality of life: A randomized controlled trial
Issued Date
2012-09-01
Resource Type
ISSN
18726968
03038467
03038467
Other identifier(s)
2-s2.0-84864283463
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Clinical Neurology and Neurosurgery. Vol.114, No.7 (2012), 866-870
Suggested Citation
Pakaratee Chaiyawat, Kongkiat Kulkantrakorn Effectiveness of home rehabilitation program for ischemic stroke upon disability and quality of life: A randomized controlled trial. Clinical Neurology and Neurosurgery. Vol.114, No.7 (2012), 866-870. doi:10.1016/j.clineuro.2012.01.018 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/14662
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Effectiveness of home rehabilitation program for ischemic stroke upon disability and quality of life: A randomized controlled trial
Author(s)
Other Contributor(s)
Abstract
Background: To develop and examine the effectiveness of individual 6-month home rehabilitation program in ischemic stroke patients upon disability and quality of life at 2 years. Methods: This is a prospective randomized controlled trial (RCT) in 60 patients with recent ischemic stroke. They were randomly assigned to receive either home rehabilitation program once a month for 6 months with audiovisual materials (intervention group) or usual care (control group). We collected outcome data after discharge from the hospital until 2 years. The Barthel index (BI), the modified Rankin Scale (mRS) and utility index (EQ-5D) were measured for function, disability and quality of life respectively. Results: At 2 years, the BI was significantly improved in the intervention group more than the control group: 97.2 ± 2.8 vs. 76.4 ± 9.4, p < 0.001. The good outcome, defined as BI 95-100, or mRS 0 or 1. For BI, there were 29 patients (96.7%) in intervention group vs 12 patients (42.9%) in usual care group (95% CI, 42.0, 85.0, p = 0.03). For mRS, there were 28 patients (93.3%) in intervention group vs 9 patients (32.1%) in usual care group (95% CI, 38.2, 87.0, p = 0.02). Number needed to treat for good outcome in mRS was 2.0 (95% CI: 1.0, 1.3). The mean (SD) of utility index in intervention group and control group were 0.9 ± 0.02 and 0.7 ± 0.04 respectively (p = 0.03). There was no significant interaction in baseline characteristics and treatment outcome. Conclusions: Early home rehabilitation program in the first 6 months period after ischemic stroke leads to more rapid improvement in function, reducing disability and increase quality of life than usual care. © 2012 Elsevier B.V.