Publication: Stimulation of gastric mucus and protein secretion by cytochalasin E in rats
Issued Date
1986-01-01
Resource Type
ISSN
03091651
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2-s2.0-0022977150
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Mahidol University
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SCOPUS
Bibliographic Citation
Cell Biology International Reports. Vol.10, No.9 (1986), 707-716
Suggested Citation
Pawinee Piyachaturawat, Wisuda Suvitayawat, Thirayudh Glinsukon Stimulation of gastric mucus and protein secretion by cytochalasin E in rats. Cell Biology International Reports. Vol.10, No.9 (1986), 707-716. doi:10.1016/0309-1651(86)90128-1 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/9669
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Title
Stimulation of gastric mucus and protein secretion by cytochalasin E in rats
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Abstract
Effects of cytochalasin E on the secretion of mucus and protein were investigated in gastric fistula rats. Direct exposure of the gastric mucosa to cytochalasin E (5-20 μg/ml) significantly stimulated the secretory rate of soluble mucus and protein in pentagastrin-stimulated rats. The amount of surface mucus gel was also increased. The stimulatory effect was increased with increased concentrations of cytochalasin. Histological study suggests that the cytochalasin stimulated the release of mucus from the cell. The increase in secretory rate of protein was not due to an increase of pepsin secretion but rather was the consequence of the increase in mucus secretion. © 1986.