Publication: Double-dose ivermectin vs albendazole for the treatment of gnathostomiasis
12
Issued Date
2005-05-01
Resource Type
ISSN
01251562
Other identifier(s)
2-s2.0-24944479126
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Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Southeast Asian Journal of Tropical Medicine and Public Health. Vol.36, No.3 (2005), 650-652
Suggested Citation
Ponganant Nontasut, Bo A. Claesson, Paron Dekumyoy, Wallop Pakdee, Sukvannee Chullawichit Double-dose ivermectin vs albendazole for the treatment of gnathostomiasis. Southeast Asian Journal of Tropical Medicine and Public Health. Vol.36, No.3 (2005), 650-652. Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/16992
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Title
Double-dose ivermectin vs albendazole for the treatment of gnathostomiasis
Abstract
A comparative study was performed for the treatment of gnathostomiasis patients with ivermectin 0.2 mg/kg for 2 days in 15 patients vs albendazole 400 mg twice daily for 21 days in 14 patients. The ivermectin and albendazole gave cure rates of 100% and 78.5%, respectively, however the difference was not statistically significant between the two drugs (Fisher's exact, p=0.0996). One year after treatment, the patients who had no migratory swellings and a drop in ELISA titers or a negative immunoblot test were considered to be cured. The side effect of ivermectin for two days was dizziness. The side effects of albendazole were nausea, dizziness, and an increased alkaline phosphatase.