Publication: Towards harmonization of microscopy methods for malaria clinical research studies
Issued Date
2020-09-04
Resource Type
ISSN
14752875
Other identifier(s)
2-s2.0-85090510189
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Malaria Journal. Vol.19, No.1 (2020)
Suggested Citation
Mehul Dhorda, El Hadji Ba, J. Kevin Baird, John Barnwell, David Bell, Jane Y. Carter, Arjen Dondorp, Lenny Ekawati, Michelle Gatton, Iveth González, Philippe J. Guérin, Sandra Incardona, Ken Lilley, Didier Menard, François Nosten, Peter Obare, Bernhards Ogutu, Piero L. Olliaro, Ric N. Price, Stéphane Proux, Andrew R. Ramsay, John C. Reeder, Kamolrat Silamut, Cheikh Sokhna Towards harmonization of microscopy methods for malaria clinical research studies. Malaria Journal. Vol.19, No.1 (2020). doi:10.1186/s12936-020-03352-z Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/59113
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Towards harmonization of microscopy methods for malaria clinical research studies
Author(s)
Mehul Dhorda
El Hadji Ba
J. Kevin Baird
John Barnwell
David Bell
Jane Y. Carter
Arjen Dondorp
Lenny Ekawati
Michelle Gatton
Iveth González
Philippe J. Guérin
Sandra Incardona
Ken Lilley
Didier Menard
François Nosten
Peter Obare
Bernhards Ogutu
Piero L. Olliaro
Ric N. Price
Stéphane Proux
Andrew R. Ramsay
John C. Reeder
Kamolrat Silamut
Cheikh Sokhna
El Hadji Ba
J. Kevin Baird
John Barnwell
David Bell
Jane Y. Carter
Arjen Dondorp
Lenny Ekawati
Michelle Gatton
Iveth González
Philippe J. Guérin
Sandra Incardona
Ken Lilley
Didier Menard
François Nosten
Peter Obare
Bernhards Ogutu
Piero L. Olliaro
Ric N. Price
Stéphane Proux
Andrew R. Ramsay
John C. Reeder
Kamolrat Silamut
Cheikh Sokhna
Other Contributor(s)
Oxford University Clinical Research Unit
Institut Pasteur du Cambodge
Institut de Recherche pour le Développement Dakar
Kenya Medical Research Institute
Amref Health Africa
Shoklo Malaria Research Unit
Menzies School of Health Research
Centers for Disease Control and Prevention
Mahidol University
Queensland University of Technology QUT
School of Medicine
Nuffield Department of Medicine
UNICEF
Terre des Hommes Foundation
Independent Consultant
FIND
Australian Defence Force Malaria and Infectious Disease Institute
WorldWide Antimalarial Resistance Network
Worldwide Antimalarial Resistance Network
Institut Pasteur du Cambodge
Institut de Recherche pour le Développement Dakar
Kenya Medical Research Institute
Amref Health Africa
Shoklo Malaria Research Unit
Menzies School of Health Research
Centers for Disease Control and Prevention
Mahidol University
Queensland University of Technology QUT
School of Medicine
Nuffield Department of Medicine
UNICEF
Terre des Hommes Foundation
Independent Consultant
FIND
Australian Defence Force Malaria and Infectious Disease Institute
WorldWide Antimalarial Resistance Network
Worldwide Antimalarial Resistance Network
Abstract
© 2020 The Author(s). Microscopy performed on stained films of peripheral blood for detection, identification and quantification of malaria parasites is an essential reference standard for clinical trials of drugs, vaccines and diagnostic tests for malaria. The value of data from such research is greatly enhanced if this reference standard is consistent across time and geography. Adherence to common standards and practices is a prerequisite to achieve this. The rationale for proposed research standards and procedures for the preparation, staining and microscopic examination of blood films for malaria parasites is presented here with the aim of improving the consistency and reliability of malaria microscopy performed in such studies. These standards constitute the core of a quality management system for clinical research studies employing microscopy as a reference standard. They can be used as the basis for the design of training and proficiency testing programmes as well as for procedures and quality assurance of malaria microscopy in clinical research.