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Hexane extract of seaweed caulerpa lentillifera inhibits cell proliferation and induces apoptosis of human glioblastoma cells

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dc.contributor.authorVaritta Tanawooten_US
dc.contributor.authorPornpun Vivithanapornen_US
dc.contributor.authorTanapan Siangchamen_US
dc.contributor.authorKrai Meemonen_US
dc.contributor.authorNakorn Niamnonten_US
dc.contributor.authorPrasert Sobhonen_US
dc.contributor.authorMontakan Tamtinen_US
dc.contributor.authorKant Sangpairojen_US
dc.contributor.otherFaculty of Medicine Ramathibodi Hospital, Mahidol Universityen_US
dc.contributor.otherFaculty of Medicine, Thammasat Universityen_US
dc.contributor.otherMahidol Universityen_US
dc.contributor.otherBurapha Universityen_US
dc.contributor.otherKing Mongkut's University of Technology Thonburien_US
dc.contributor.otherPhetcha Buri Coastal Aquaculture Research and Development Centeren_US
dc.date.accessioned2022-08-04T07:57:37Z
dc.date.available2022-08-04T07:57:37Z
dc.date.issued2021-04-01en_US
dc.description.abstractGlioblastoma is one the most aggressive types of brain cancers resistant to conventional anti-neoplastic drugs. Marine seaweeds possess valuable bioactive compounds for disease prevention and therapy, including for a number of cancers. Caulerpa lentillifera is a tropical marine seaweed containing various minerals and bioactive ingredients. This study demonstrated the activity of C. lentillifera hexane extract (CLHE) against A172 human glioblastoma cells. The extract exerted growth-inhibitory effects by inhibiting cell proliferation and inducing apoptosis. CLHE also induced ROS accumulation and altered mitochondrial membrane potential in A172 cells. Taken together, CLHE might be a potential anticancer agent for use against glioblastoma.en_US
dc.identifier.citationScience and Technology Asia. Vol.26, No.2 (2021), 128-137en_US
dc.identifier.issn25869027en_US
dc.identifier.other2-s2.0-85109861701en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/20.500.14594/75687
dc.rightsMahidol Universityen_US
dc.rights.holderSCOPUSen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85109861701&origin=inwarden_US
dc.subjectAgricultural and Biological Sciencesen_US
dc.subjectMathematicsen_US
dc.subjectMultidisciplinaryen_US
dc.titleHexane extract of seaweed caulerpa lentillifera inhibits cell proliferation and induces apoptosis of human glioblastoma cellsen_US
dc.typeArticleen_US
dspace.entity.typePublication
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85109861701&origin=inwarden_US

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