Publication: Ecologic risk factor investigation of clusters of avian influenza a (H5N1) virus infection in Thailand
Issued Date
2009-06-05
Resource Type
ISSN
00221899
DOI
Other identifier(s)
2-s2.0-67650446504
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Journal of Infectious Diseases. Vol.199, No.12 (2009), 1735-1743
Suggested Citation
Thanawat Tiensin, Syed Sayeem Uddin Ahmed, Suvichai Rojanasthien, Thaweesak Songserm, Parntep Ratanakorn, Kridsada Chaichoun, Wantanee Kalpravidh, Surapong Wongkasemjit, Tuangthong Patchimasiri, Karoon Chanachai, Weerapong Thanapongtham, Suwit Chotinan, Arjan Stegeman, Mirjam Nielen Ecologic risk factor investigation of clusters of avian influenza a (H5N1) virus infection in Thailand. Journal of Infectious Diseases. Vol.199, No.12 (2009), 1735-1743. doi:10.1086/599207 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/28048
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Ecologic risk factor investigation of clusters of avian influenza a (H5N1) virus infection in Thailand
Abstract
This study was conducted to investigate space and time clusters of highly pathogenic avian influenza A (H5N1) virus infection and to determine risk factors at the subdistrict level in Thailand. Highly pathogenic avian influenza A (H5N1) was diagnosedin1890 poultry flocks located in 953 subdistricts during 2004-2007. The ecologic risk for H5N1 virus infection was assessed on the basis of a spatial-based case-control study involving 824 case subdistricts and 3296 control subdistricts from 6 study periods. Risk factors investigated in clustered areas of H5N1 included human and animal demographic characteristics, poultry production systems, and wild birds and their habitats. Six variables remained statistically significant in the final model: flock density of backyard chickens (odds ratio [OR], 0.98), flock density of fighting cocks (OR, 1.02), low and high human density (OR, 0.60), presence of quail flocks (OR, 1.21), free-grazing duck flocks (OR, 2.17), and a poultry slaughterhouse (OR, 1.33). We observed a strong association between subdistricts with H5N1 virus-infected poultry flocks and evidence of prior and concomitant H5N1 infection in wild birds in the same subdistrict. © 2009 by the Infectious Diseases Society of America.