Publication: Influenza AH1N1 2009 pneumonia in kidney transplant recipients: Characteristics and outcomes following high-dose oseltamivir exposure
Issued Date
2010-04-01
Resource Type
ISSN
13993062
13982273
13982273
Other identifier(s)
2-s2.0-77950555049
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Mahidol University
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SCOPUS
Bibliographic Citation
Transplant Infectious Disease. Vol.12, No.2 (2010), 127-131
Suggested Citation
S. P. Watcharananan, T. Suwatanapongched, P. Wacharawanichkul, W. Chantratitaya, V. Mavichak, S. B. Mossad Influenza AH1N1 2009 pneumonia in kidney transplant recipients: Characteristics and outcomes following high-dose oseltamivir exposure. Transplant Infectious Disease. Vol.12, No.2 (2010), 127-131. doi:10.1111/j.1399-3062.2010.00493.x Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/29718
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Title
Influenza AH1N1 2009 pneumonia in kidney transplant recipients: Characteristics and outcomes following high-dose oseltamivir exposure
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Abstract
We report 2 cases of severe pneumonia due to the novel pandemic influenza AH1N1 2009 in kidney transplant recipients. Our patients initially experienced influenza-like illness that rapidly progressed to severe pneumonia within 48 h. The patients became hypoxic and required non-invasive ventilation. The novel influenza AH1N1 2009 was identified from their nasal swabs. These cases were treated successfully with a relatively high dose of oseltamivir, adjusted for their renal function. Clinical improvement was documented only after a week of antiviral therapy. Despite early antiviral treatment, we showed that morbidity following novel pandemic influenza AH1N1 2009 infection is high among kidney transplant recipients. © 2010 John Wiley & Sons A/S.