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Well-differentiated fetal adenocarcinoma of the lung mimicking adenoid cystic carcinoma on fine needle aspiration: A case report

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dc.contributor.authorVilasinee Rerkpichaisuthen_US
dc.contributor.authorJennifer A. Collinsen_US
dc.contributor.authorThiraphon Boonyaarunnateen_US
dc.contributor.authorSyed Z. Alien_US
dc.contributor.otherMahidol Universityen_US
dc.contributor.otherThe Johns Hopkins School of Medicineen_US
dc.date.accessioned2018-12-11T03:18:23Z
dc.date.accessioned2019-03-14T08:01:58Z
dc.date.available2018-12-11T03:18:23Z
dc.date.available2019-03-14T08:01:58Z
dc.date.issued2016-11-01en_US
dc.description.abstract© 2016 Wiley Periodicals, Inc. Well-differentiated fetal adenocarcinoma (WDFA) of the lung is a rare variant of adenocarcinoma with an unusual morphology. Although the histologic features of this rare neoplasm have been well established, there is a deficit in the literature with regards to its discrete cytomorphologic features. We report the fine needle aspiration (FNA) findings of a case of this unusual malignancy in a 44-year-old man with an incidental lung nodule. FNA revealed three-dimensional clusters of epithelial cells with scant cytoplasm, hyperchromatic nuclei that are associated with an extracellular metachromatic matrix. The original cytology report was signed out as an epithelial neoplasm favor adenoid cystic carcinoma. Consequently, a wedge resection of the lung was done and the histologic diagnosis was WDFA of the lung. The findings of minimal nuclear atypia in association with focally abundant spheres of extracellular matrix can mimic adenoid cystic carcinoma. WDFA has good prognosis and therefore, pre-operative cytologic diagnosis is critical to clinical management. We present the cytomorphologic features of this neoplasm with particular emphasis on a potential diagnostic pitfall of this rare entity. Diagn. Cytopathol. 2016;44:917–920. © 2016 Wiley Periodicals, Inc.en_US
dc.identifier.citationDiagnostic Cytopathology. Vol.44, No.11 (2016), 917-920en_US
dc.identifier.doi10.1002/dc.23526en_US
dc.identifier.issn10970339en_US
dc.identifier.issn87551039en_US
dc.identifier.other2-s2.0-84978164213en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14594/41028
dc.rightsMahidol Universityen_US
dc.rights.holderSCOPUSen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84978164213&origin=inwarden_US
dc.subjectMedicineen_US
dc.titleWell-differentiated fetal adenocarcinoma of the lung mimicking adenoid cystic carcinoma on fine needle aspiration: A case reporten_US
dc.typeArticleen_US
dspace.entity.typePublication
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84978164213&origin=inwarden_US
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