Publication: Intracranial hemorrhage in infants due to acquired prothrombin complex deficiency
1
Issued Date
1974-01-01
Resource Type
ISSN
00223085
Other identifier(s)
2-s2.0-0016136947
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Journal of Neurosurgery. Vol.41, No.1 (1974), 14-19
Suggested Citation
P. Visudhiphan, P. Bhanchet, C. Lakanapichanchat, S. Chiemchanya Intracranial hemorrhage in infants due to acquired prothrombin complex deficiency. Journal of Neurosurgery. Vol.41, No.1 (1974), 14-19. doi:10.3171/jns.1974.41.1.0014 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/10709
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Intracranial hemorrhage in infants due to acquired prothrombin complex deficiency
Other Contributor(s)
Abstract
The authors report 8 infants who had acute intracranial bleeding after the third week of life, in the absence of known trauma. When first seen each was moribund, pale, and had a tense anterior fontanel; half of the cases had associated ecchymoses. Spinal and subdural taps yielded large amounts of bloody fluid. Coagulation studies indicated a severe lack of factors involved in prothrombin complex formation. The clotting indices were sufficiently low to account for spontaneous bleeding. Satisfactory clinical and laboratory results were demonstrated after subdural and spinal taps combined with IV vitamin K and fresh blood transfusion to correct the coagulation defect and anemia.