Clinical and Diagnostic Laboratory Immunology. Vol.11, No.6 (2004), 1194-1197
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Catrin E. Moore, Shelley Segal, Anthony R. Berendt, Adrian V.S. Hill, Nicholas P.J. Day Lack of association between toll-like receptor 2 polymorphisms and susceptibility to severe disease caused by Staphylococcus aureus. Clinical and Diagnostic Laboratory Immunology. Vol.11, No.6 (2004), 1194-1197. doi:10.1128/CDLI.11.6.1194-1197.2004 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/21140
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Lack of association between toll-like receptor 2 polymorphisms and susceptibility to severe disease caused by Staphylococcus aureus
To investigate a putative link between genetically determined variations in Toll-like receptor 2 (TLR2) and the occurrence of severe Staphylococcus aureus infection, the functional Arg753Gln single-nucleotide polymorphism and the GT repeat microsatellite in the TLR2 gene were examined in a large case-control study. No associations with disease or mortality attributable to these features were found.