Journal of Tropical Medicine and Hygiene. Vol.79, No.6 (1976), 116-119
Suggested Citation
S. Boonpucknavig, S. Wongsawang, V. Boonpucknavig, N. Bhamarapravati Serum soluble malarial antigens and immune complex nephritis in Plasmodium berghei infected mice. Journal of Tropical Medicine and Hygiene. Vol.79, No.6 (1976), 116-119. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/10869
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Serum soluble malarial antigens and immune complex nephritis in Plasmodium berghei infected mice
Swiss albino mice infected with Plasmodium berghei berghei showed the serum soluble malarial antigen and antibody on day 10 of infection onward. Immune complex nephritis in these mice developed on the seventh day after inoculation. The infected kidneys revealed the deposition of mouse gamma globulin, mouse β1C globulin and malaria antigen along the capillary wall of the glomeruli. Proteinuria was detected on seventh day of infection. Serum soluble malarial antigen in probably responsible for forming the soluble immune complex which causes glomerulonephritis in infected mice.