Publication: Effect of essential oils prepared from thai culinary herbs on sessile candida albicans cultures
Issued Date
2016-09-01
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ISSN
18804926
13434934
13434934
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2-s2.0-84990872389
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Mahidol University
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SCOPUS
Bibliographic Citation
Journal of Oral Science. Vol.58, No.3 (2016), 365-371
Suggested Citation
Ray S. Hovijitra, Suwan Choonharuangdej, Theerathavaj Srithavaj Effect of essential oils prepared from thai culinary herbs on sessile candida albicans cultures. Journal of Oral Science. Vol.58, No.3 (2016), 365-371. doi:10.2334/josnusd.15-0736 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/43553
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Title
Effect of essential oils prepared from thai culinary herbs on sessile candida albicans cultures
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Abstract
© 2016, Sichuan University Press. All rights reserved. Although medicinal herbs with fungicidal effects have been ubiquitously employed in traditional medicine, such effects of culinary herbs and spices still have to be elucidated. Therefore, it is noteworthy to determine the antifungal efficacy of some edible herbs used in Thai cuisine against sessile Candida albicans cultures, and to inquire if they can be further utilized as naturally-derived antifungals. Fourteen essential oils extracted from Thai culinary herbs and spices were tested for their antifungal activity against C. albicans using the agar disk diffusion method followed by broth micro-dilution method for the determination of minimum inhibitory concentration (MIC) and minimum fungicidal concentration. The oils with potent antifungal effects against planktonic fungi were then assessed for their effect against sessile fungus (adherent organisms and established biofilm culture). MIC of the oils against sessile C. albicans was evaluated by 2,3-bis-(2-methoxy-4-nitro- 5-sulfophenyl)-2H-tetrazolium-5-carboxanilide reduction assay. All selected culinary herbs and spices, except galangal, garlic, and turmeric, exhibited inhibitory effects on planktonic yeast cells. Cinnamon bark and sweet basil leaf essential oils exhibited potent fungicidal effect on planktonic and sessile fungus. Sessile MICs were 8-16 times higher than planktonic MICs. Consequently, both cinnamon bark and sweet basil leaf herbal oils seem to be highly effective anti-Candida choices.