The role of apoB measurement in Type 2 diabetic patients

Abstract

© 2015 Future Medicine Ltd. Aims: ApoB and non-HDL-C more accurately quantify cardiovascular risk than LDL-C; however, controversies exist over which is more clinically useful. We determined how well non-HDL-C targets predicted the attainment of apoB goals. Materials & Methods: In this cross-sectional study of Type 2 diabetic patients who achieved LDL-C <100 mg/dl, apoB and non-HDL-C concentrations, and the accuracy of non-HDL-C targets against apoB goals were determined. Results: Positive predictive values of non-HDL-C goals in predicting attainment of apoB goals were 90.3%, but were reduced in patients with hypertriglyceridemia or coronary heart disease (CHD). Conclusion: ApoB measurement could be useful in evaluating cardiovascular risk in diabetic subjects with hypertriglyceridemia or CHD who have already achieved LDL-C and non-HDL-C targets.