Journal of the Medical Association of Thailand. Vol.57, No.5 (1974), 242-247
Suggested Citation
S. Wasantapruek, M. Kruatrachue, A. Piankijagum, K. Limpongs Blood coagulation and platelet agglutinin studies in acute falciparum malaria. Journal of the Medical Association of Thailand. Vol.57, No.5 (1974), 242-247. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/10654
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Blood coagulation and platelet agglutinin studies in acute falciparum malaria
Thrombocytopenia was demonstrated in 72 out of 109 acute uncomplicated cases of falciparum malaria. Coagulation tests were within normal limits. A significant increase in fibrinogen level was observed. The mechanism of thrombocytopenia appeared not to be due to decreased bone marrow platelet production or being platelet destroyed in the process of intravascular coagulation. Thrombocytopenia was negatively correlated with the degree of hepatomegaly which perhaps suggested the role of the liver in the mechanism of thrombocytopenia. Platelet agglutinin was observed in 43 out of 84 cases.