Publication: Treatment of nephrotic syndrome with levamisole
Issued Date
1980-01-01
Resource Type
ISSN
00223476
Other identifier(s)
2-s2.0-0018830936
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Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
The Journal of Pediatrics. Vol.96, No.3 PART 1 (1980), 490-493
Suggested Citation
P. Tanphaichitr, D. Tanphaichitr, J. Sureeratanan, S. Chatasingh Treatment of nephrotic syndrome with levamisole. The Journal of Pediatrics. Vol.96, No.3 PART 1 (1980), 490-493. doi:10.1016/S0022-3476(80)80707-4 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/11160
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Title
Treatment of nephrotic syndrome with levamisole
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Abstract
Considerable evidence suggests a role of abnormal T-cell lymphocyte functions in the pathogenesis of minimal lesion nephrotic syndrome. The mean ± SD T-cell lymphocytes as determined by %E-rosettes among 10 children after 24 to 84 months of complete remission was 66.7±4.5; this is statistically different from that of seven children with minimal lesion nephrotic syndrome during relapse, 33.5±9.5 (P < 0.01). After levamisole therapy at 1.5 to 3.9 mg/kg/dose twice weekly for one to six months, the mean ±SD %E-rosettes in the latter group was 69.3±3.9, which is not statistically different from that in the group with complete remission after conventional treatment with steroids. Those treated with levamisole also had a complete remission without any side effects. © 1980 The C. V. Mosby Company.