Publication:
Comorbidities frequency in takotsubo syndrome: An international collaborative systematic review including 1109 patients

Issued Date

2015-06-01

Resource Type

Article

ISSN

15557162
00029343

DOI

10.1016/j.amjmed.2015.01.016

Other identifier(s)

2-s2.0-84930384373

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

American Journal of Medicine. Vol.128, No.6 (2015), 654.e11-654.e19

Suggested Citation

Francesco Pelliccia, Guido Parodi, Cesare Greco, David Antoniucci, Roman Brenner, Eduardo Bossone, Luca Cacciotti, Alessandro Capucci, Rodolfo Citro, Clément Delmas, Federico Guerra, Costin N. Ionescu, Olivier Lairez, Maiteder Larrauri-Reyes, Pil Hyung Lee, Nicolas Mansencal, Giuseppe Marazzi, Christos G. Mihos, Olivier Morel, Holger M. Nef, Ivan J. Nunez Gil, Ilaria Passaseo, Andres M. Pineda, Giuseppe Rosano, Orlando Santana, Franziska Schneck, Bong Gun Song, Jae Kwan Song, Andrew W. Teh, Patompong Ungprasert, Alberto Valbusa, Andreas Wahl, Tetsuro Yoshida, Carlo Gaudio, Juan Carlos Kaski Comorbidities frequency in takotsubo syndrome: An international collaborative systematic review including 1109 patients. American Journal of Medicine. Vol.128, No.6 (2015), 654.e11-654.e19. doi:10.1016/j.amjmed.2015.01.016 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/36430

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Title

Comorbidities frequency in takotsubo syndrome: An international collaborative systematic review including 1109 patients

Author(s)

Francesco Pelliccia
 Guido Parodi
 Cesare Greco
 David Antoniucci
 Roman Brenner
 Eduardo Bossone
 Luca Cacciotti
 Alessandro Capucci
 Rodolfo Citro
 Clément Delmas
 Federico Guerra
 Costin N. Ionescu
 Olivier Lairez
 Maiteder Larrauri-Reyes
 Pil Hyung Lee
 Nicolas Mansencal
 Giuseppe Marazzi
 Christos G. Mihos
 Olivier Morel
 Holger M. Nef
 Ivan J. Nunez Gil
 Ilaria Passaseo
 Andres M. Pineda
 Giuseppe Rosano
 Orlando Santana
 Franziska Schneck
 Bong Gun Song
 Jae Kwan Song
 Andrew W. Teh
 Patompong Ungprasert
 Alberto Valbusa
 Andreas Wahl
 Tetsuro Yoshida
 Carlo Gaudio
 Juan Carlos Kaski

Other Contributor(s)

Universita degli Studi di Roma La Sapienza
 Azienda Ospedaliera Careggi
 Kantonsspital Olten
 University Hospital San Giovanni di Dio e Ruggi d'Aragona
 Ospedale Madre G. Vannini
 Universita Politecnica delle Marche
 Hopital de Rangueil
 Yale University
 Mount Sinai Medical Center Miami Beach
 University of Ulsan, College of Medicine
 Universite de Versailles Saint-Quentin-en-Yvelines
 IRCCS San Raffaele Pisana
 Pôle d'Activité Medico-chirurgicale Cardiovasculaire
 Justus Liebig University Giessen
 Hospital Clinico San Carlos de Madrid
 St George's University of London
 Konkuk University Hospital
 Monash University
 Austin Hospital
 Mahidol University
 IRCCS Istituto Giannina Gaslini - Ospedale Pediatrico
 UniversitatsSpital Bern
 Onga Hospital

Abstract

© 2015 Elsevier Inc. All rights reserved. Background To identify predisposing factors that can result in the onset of takotsubo syndrome, we performed an international, collaborative systematic review focusing on clinical characteristics and comorbidities of patients with takotsubo syndrome. Methods We searched and reviewed cited references up to August 2013 to identify relevant studies. Corresponding authors of selected studies were contacted and asked to provide additional quantitative details. Data from each study were extracted by 2 independent reviewers. The cumulative prevalence of presenting features and comorbidities was assessed. Nineteen studies whose authors sent the requested information were included in the systematic review, with a total of 1109 patients (951 women; mean age, 59-76 years). Evaluation of risk factors showed that obesity was present in 17% of patients (range, 2%-48%), hypertension in 54% (range, 27%-83%), dyslipidemia in 32% (range, 7%-59%), diabetes in 17% (range, 4%-34%), and smoking in 22% (range, 6%-49%). Emotional stressors preceded takotsubo syndrome in 39% of patients and physical stressors in 35%. The most common comorbidities were psychological disorders (24%; range, 0-49%), pulmonary diseases (15%; range, 0-22%), and malignancies (10%; range, 4%-29%). Other common associated disorders were neurologic diseases (7%; range, 0-22%), chronic kidney disease (7%; range, 2%-27%), and thyroid diseases (6%; range, 0-37%). Conclusions Patients with takotsubo syndrome have a relevant prevalence of cardiovascular risk factors and associated comorbidities. Such of associations needs to be evaluated in further studies.

Keyword(s)

Medicine

Availability

URI

https://repository.li.mahidol.ac.th/handle/123456789/36430

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