Amyloidosis and respiratory tract involvement: Report of two cases

Abstract

Amyloidosis is a group of diseases in which amyloid deposit in the extracellular space in an abnormal insoluble fibrillar form. The most important amyloid precursors are immunoglobulin light chain (AL) and serum amyloid-associated protein (AA). Amyloidosis can manifest as localized or systemic disease and respiratory system is one of the target organs that can be involved by amyloid. The authors report two cases of pulmonary amyloidosis presented with diffuse interstitial pulmonary amyloidosis and tracheobronchial involvement.