Publication: Chronic Liver Disease: Differences in Autoimmune Serological Reactions Between Australians and Asians
Issued Date
1973-12-01
Resource Type
ISSN
00071447
Other identifier(s)
2-s2.0-0015806992
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
British Medical Journal. Vol.4, No.5891 (1973), 517-519
Suggested Citation
Senga Whittingham, Ian R. Mackay, R. S. Thanabalasundrum, H. K. Chuttani, R. Manjuran, C. S. Seah, M. Yu, V. Viranuvatti Chronic Liver Disease: Differences in Autoimmune Serological Reactions Between Australians and Asians. British Medical Journal. Vol.4, No.5891 (1973), 517-519. doi:10.1136/bmj.4.5891.517 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/10189
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Title
Chronic Liver Disease: Differences in Autoimmune Serological Reactions Between Australians and Asians
Abstract
A total of 164 patients from Australia, Ceylon, India, Singapore, and Thailand were studied for the prevalence of autoantibodies associated with “idiopathic” chronic liver disease—namely, antinuclear antibody, smooth muscle antibody, and mitochondrial antibody. The prevalence of these autoantibodies was high among patients from Australia (55%), but was low among patients from Ceylon (14%), India (11%), Singapore (0%), and Thailand (8%). There are variations in types of hepatitis and cirrhosis between races, and this applies particularly to the type associated with autoimmune markers. This may be related to genetic differences that have evolved between peoples of European and Asian descent. © 1973, British Medical Journal Publishing Group. All rights reserved.