Publication: Diketopiperazines and phthalides from a marine derived fungus of the order pleosporales
Issued Date
2008-01-01
Resource Type
ISSN
00320943
Other identifier(s)
2-s2.0-39149083695
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Mahidol University
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SCOPUS
Bibliographic Citation
Planta Medica. Vol.74, No.1 (2008), 69-72
Suggested Citation
Vilailak Prachyawarakorn, Chulabhorn Mahidol, Sanya Sureram, Suwannee Sangpetsiripan, Suthep Wiyakrutta, Somsak Ruchirawat, Prasat Kittakoop Diketopiperazines and phthalides from a marine derived fungus of the order pleosporales. Planta Medica. Vol.74, No.1 (2008), 69-72. doi:10.1055/s-2007-993783 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/19010
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Title
Diketopiperazines and phthalides from a marine derived fungus of the order pleosporales
Abstract
Five metabolites, (Z)-6-benzylidene-3-hydroxymethyl-1,4-dimethyl-3- methylsulfanylpiperazine-2,5-dione (1), (3S,3′R)-3-(3′-hydroxybutyl) -7-methoxyphthalide (2), (S)-3-butyl-7-methoxyphthalide (3), (3R,6R)-bisdethiodi(methylthio)-hyalodendrin (4), and bis-N-norgliovictin (5), were isolated from the culture broth of the marine derived fungus of the order Pleosporales strain CRIF2. Compounds 1 and 2 are new fungal metabolites, while 3 was isolated for the first time as a natural product. Compounds 1,3, and 4 exhibited only weak cytotoxic activity, while 5 was inactive at 50 μg/mL. © Georg Thieme Verlag KG Stuttgart.