Publication: Nano-Coating of Metronidazole on Dental Implants for Antibacterial Application
Issued Date
2019-02-13
Resource Type
ISSN
21596972
21596964
21596964
Other identifier(s)
2-s2.0-85063065879
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
IEEE International Conference on Nano/Molecular Medicine and Engineering, NANOMED. Vol.2018-December, (2019), 59-62
Suggested Citation
Norased Nasongkla, Chayanan Tanesanukul, Sirawit Nilyok, Nattarat Wongsuwan, Salunya Tancharoen, Supassara Nilanont Nano-Coating of Metronidazole on Dental Implants for Antibacterial Application. IEEE International Conference on Nano/Molecular Medicine and Engineering, NANOMED. Vol.2018-December, (2019), 59-62. doi:10.1109/NANOMED.2018.8641568 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/50257
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Nano-Coating of Metronidazole on Dental Implants for Antibacterial Application
Other Contributor(s)
Abstract
© 2018 IEEE. Nano-coating on dental implants for antibacterial applications was studied for the inhibition of Porphyromonas gingivalis biofilm formation. In this work, metronidazole, an antibacterial agent, was loaded in niosomes and coated on dental implants using layer-by-layer dip coating technique with poly(lactic acid) (PLA). Drug loaded niosomes was fabricated via thin film hydration method. The niosomes was coated by varying the dipping cycle. The dental implants were coated for 90 cycles and were characterized further to determine drug loading content, release profile and inhibition zone. In detail, average drug loading content was 22.85 ± 1.56 μg. Antibacterial study showed that Metronidazole release could inhibit bacteria. Therefore, the result suggested that the layer-by-layer dip coating on dental implants for antibacterial application could be potentially elevated by using niosomes.