Publication: Patients with schizophrenia have a higher risk of psoriasis: A systematic review and meta-analysis
Issued Date
2018-01-01
Resource Type
ISSN
18727123
01651781
01651781
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2-s2.0-85033379925
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Mahidol University
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SCOPUS
Bibliographic Citation
Psychiatry Research. Vol.259, (2018), 422-426
Suggested Citation
Patompong Ungprasert, Karn Wijarnpreecha, Wisit Cheungpasitporn Patients with schizophrenia have a higher risk of psoriasis: A systematic review and meta-analysis. Psychiatry Research. Vol.259, (2018), 422-426. doi:10.1016/j.psychres.2017.11.021 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/47193
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Title
Patients with schizophrenia have a higher risk of psoriasis: A systematic review and meta-analysis
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Abstract
© 2017 Elsevier B.V. Recent studies have suggested an increased risk of psoriasis among patients with schizophrenia although the results are still inconclusive. This systematic review and meta-analysis of cohort and case-control studies that compared the risk psoriasis among patients with schizophrenia versus subjects without schizophrenia was conducted to better characterize the risk. Pooled relative risks and 95% confidence intervals from the included studies were calculated using a random-effect, generic inverse variance method of DerSimonian and Laird. After a comprehensive literature review, 2 retrospective cohort studies and 4 case-control studies with approximately 6.1 million participants were identified. The meta-analysis found that the risk of psoriasis among patients with schizophrenia was significantly higher than non-schizophrenia subjects. Subgroup analysis by study design revealed a significantly higher risk in both cohort study and case-control study subgroup.