Publication: Pharmacokinetics of oral doxycycline during combination treatment of severe falciparum malaria
Issued Date
2005-04-01
Resource Type
ISSN
00664804
Other identifier(s)
2-s2.0-16244414614
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Mahidol University
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SCOPUS
Bibliographic Citation
Antimicrobial Agents and Chemotherapy. Vol.49, No.4 (2005), 1622-1625
Suggested Citation
Paul N. Newton, Jean François Chaulet, Alan Brockman, Wirongrong Chierakul, Arjen Dondorp, Ronatrai Ruangveerayuth, Sornchai Looareesuwan, Cyril Mounier, Nicholas J. White Pharmacokinetics of oral doxycycline during combination treatment of severe falciparum malaria. Antimicrobial Agents and Chemotherapy. Vol.49, No.4 (2005), 1622-1625. doi:10.1128/AAC.49.4.1622-1625.2005 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/17022
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Title
Pharmacokinetics of oral doxycycline during combination treatment of severe falciparum malaria
Abstract
The pharmacokinetics of oral doxycycline administered at 200 mg every 24 h were investigated in 17 patients recovering from severe Plasmodium falciparum malaria. The data suggest that the doses of doxycycline currently recommended (circa 3.5 mg/kg of body weight daily) may not be optimal. Copyright © 2005, American Society for Microbiology. All Rights Reserved.