Publication: Studies on the effect of ethyl palmitate on the inhibition of erythrophagocytosis in dogs
Issued Date
1973-12-01
Resource Type
ISSN
00383619
Other identifier(s)
2-s2.0-0015859015
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Southeast Asian Journal of Tropical Medicine and Public Health. Vol.4, No.2 (1973), 250-255
Suggested Citation
S. Areekul, Y. Chantachum, L. Suebsaeng, K. Chaovanapricha Studies on the effect of ethyl palmitate on the inhibition of erythrophagocytosis in dogs. Southeast Asian Journal of Tropical Medicine and Public Health. Vol.4, No.2 (1973), 250-255. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/10165
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Studies on the effect of ethyl palmitate on the inhibition of erythrophagocytosis in dogs
Author(s)
Other Contributor(s)
Abstract
The effect of 10% ethyl palmitate suspension on the erythrophagocytic activity of the reticuloendothelial system was studied in 9 dogs using 51 Cr labelled human red cell as a test substance. The results showed that the half disappearance times of 51 Cr labelled red cell in ethpalm dogs were prolonged indicating that ethyl palmitate depressed the erythrophagocytosis of the reticuloendothelial system. Microscopic examination also showed the degenerative changes of the livers in these dogs. In dogs receiving 20% and 30% ethyl palmitate, the liver showed necrosis with focal hemorrhage while the spleen showed no significant pathological changes. This selective hepatic necrosis induced by the ethyl palmitate in dogs was different from the results obtained in mice, rats, guineapigs and rabbits.