Publication: Serum cholesterol reduction efficacy of biscuits with added plant stanol ester
Issued Date
2015-01-01
Resource Type
ISSN
20901291
20901283
20901283
Other identifier(s)
2-s2.0-84925813805
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Cholesterol. Vol.2015, (2015)
Suggested Citation
Wantanee Kriengsinyos, Ajima Wangtong, Surat Komindr Serum cholesterol reduction efficacy of biscuits with added plant stanol ester. Cholesterol. Vol.2015, (2015). doi:10.1155/2015/353164 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/35776
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Serum cholesterol reduction efficacy of biscuits with added plant stanol ester
Author(s)
Other Contributor(s)
Abstract
© 2015 Wantanee Kriengsinyos et al. This study's aim was to test the low-density lipoprotein cholesterol- (LDL-c-) lowering efficacy of biscuits containing 2 g of plant stanols, which corresponded to 3.4 g of plant stanol esters. The biscuit is a new food format that can be consumed as a snack. In a double-blind, placebo-controlled parallel design study, 119 mildly to moderately hypercholesterolemic volunteers were randomized to plant stanol or control groups. Subjects were comparable in age, gender, lipid profiles, and body mass index. They consumed a control biscuit once a day for a two-week period, followed by a four-week intervention period that either had a plant stanol ester biscuit or a control. During the habitual diet, one biscuit per day was consumed at any time that subjects wished. Serum lipid profiles were measured at the first day of run-in, at baseline, and at the study's end. Compared to the control, the total cholesterol (TC), LDL-c, and the LDL-to-high-density lipoprotein (LDL/HDL) ratio had serum reductions of 4.9%, 6.1%, and 4.3%, respectively, and were observed after 4 weeks of biscuit consumption with added plant stanols (P < 0.05). A significantly higher reduction in LDL-c (8.9%) and LDL/HDL ratio (11.4%) was measured in those taking a plant stanol biscuit with a meal compared to those who consumed a plant stanol biscuit without other food. In conclusion, incorporating plant stanols into a biscuit is an attractive, convenient, and acceptable way to modestly lower elevated cholesterol concentrations. For optimal efficacy, biscuits should be consumed with a meal as part of a healthy diet.