Publication:
Continuous cultivation and improved drug responsiveness of Plasmodium falciparum in p-aminobenzoic acid-deficient medium

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dc.contributor.authorP. Tan ariyaen_US
dc.contributor.authorC. R. Brockelmanen_US
dc.contributor.otherMahidol Universityen_US
dc.date.accessioned2018-10-12T07:33:51Z
dc.date.available2018-10-12T07:33:51Z
dc.date.issued1983-01-01en_US
dc.description.abstractLong term cultivation of three culture lines of Plasmodium falciparum was achieved in Waymouth and RPMI media, both supplemented with 10% heat-inactivated human serum. Observations on parasite multiplication over a 6-mo period showed no difference in the rate of parasite population increase. Growth of asexual erythrocytic stages in Waymouth medium was as good as that in RPMI when measured by the rate of glucose utilization and extent of3H-isoleucine and3H-methionine incorporation. Responsiveness of the parasites to pyrimethamine and sulfadoxine was demonstrated to increase when tested in Waymouth medium because it contained no p-aminobenzoic acid to compete with the drugs.en_US
dc.identifier.citationJournal of Parasitology. Vol.69, No.2 (1983), 353-359en_US
dc.identifier.doi10.2307/3281233en_US
dc.identifier.issn00223395en_US
dc.identifier.other2-s2.0-0020631684en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/20.500.14594/30424
dc.rightsMahidol Universityen_US
dc.rights.holderSCOPUSen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0020631684&origin=inwarden_US
dc.subjectAgricultural and Biological Sciencesen_US
dc.subjectImmunology and Microbiologyen_US
dc.titleContinuous cultivation and improved drug responsiveness of Plasmodium falciparum in p-aminobenzoic acid-deficient mediumen_US
dc.typeArticleen_US
dspace.entity.typePublication
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0020631684&origin=inwarden_US

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