Publication: Ferritin-bearing T-lymphocytes and serum ferritin in patients with breast cancer
Issued Date
1988-01-01
Resource Type
ISSN
15321827
00070920
00070920
Other identifier(s)
2-s2.0-0023854365
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
British Journal of Cancer. Vol.57, No.2 (1988), 193-197
Suggested Citation
K. Pattanapanyasat, T. G. Hoy, A. Jacobs, S. Courtney, D. J.T. Webster Ferritin-bearing T-lymphocytes and serum ferritin in patients with breast cancer. British Journal of Cancer. Vol.57, No.2 (1988), 193-197. doi:10.1038/bjc.1988.41 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/15510
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Title
Ferritin-bearing T-lymphocytes and serum ferritin in patients with breast cancer
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Abstract
Flow cytometric studies of T-lymphocytes in breast cancer patients show that the number of cells bearing ferritin on their surface is significantly greater than normal. The number of ferritin-bearing T-cells does not appear to be related to the clinical stage of the disease nor to the serum ferritin concentration, though this is higher in cancer patients than in normal women. There is no difference in the number of T-cells positive for interleukin 2 or transferrin receptors nor in the absolute number of T-cells, T-helper cells and B-cells between normal women and those with breast cancer or benign breast disease. However, there is a significant increase in the level of HLA DR-positive T-cells and T-suppressor cells in breast cancer patients. While the significance of ferritin-bearing T-cells is not known an increase in their number appears to be associated with cancer. © 1988 The Macmillan Press Ltd.