Publication: Setting Our Sights on Infectious Diseases
Issued Date
2020-01-10
Resource Type
ISSN
23738227
Other identifier(s)
2-s2.0-85076754483
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
ACS Infectious Diseases. Vol.6, No.1 (2020), 3-13
Suggested Citation
Manu De Rycker, David Horn, Bree Aldridge, Richard K. Amewu, Clifton E. Barry, Frederick S. Buckner, Sarah Cook, Michael A.J. Ferguson, Nathalie Gobeau, Jennifer Herrmann, Paul Herrling, William Hope, Jennifer Keiser, Maria Jose Lafuente-Monasterio, Paul D. Leeson, Didier Leroy, Ujjini H. Manjunatha, James McCarthy, Timothy J. Miles, Valerie Mizrahi, Olena Moshynets, Jacquin Niles, John P. Overington, John Pottage, Srinivasa P.S. Rao, Kevin D. Read, Isabela Ribeiro, Lynn L. Silver, Jen Southern, Thomas Spangenberg, Shyam Sundar, Caitlin Taylor, Wes Van Voorhis, Nicholas J. White, Susan Wyllie, Paul G. Wyatt, Ian H. Gilbert Setting Our Sights on Infectious Diseases. ACS Infectious Diseases. Vol.6, No.1 (2020), 3-13. doi:10.1021/acsinfecdis.9b00371 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/53782
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Setting Our Sights on Infectious Diseases
Author(s)
Manu De Rycker
David Horn
Bree Aldridge
Richard K. Amewu
Clifton E. Barry
Frederick S. Buckner
Sarah Cook
Michael A.J. Ferguson
Nathalie Gobeau
Jennifer Herrmann
Paul Herrling
William Hope
Jennifer Keiser
Maria Jose Lafuente-Monasterio
Paul D. Leeson
Didier Leroy
Ujjini H. Manjunatha
James McCarthy
Timothy J. Miles
Valerie Mizrahi
Olena Moshynets
Jacquin Niles
John P. Overington
John Pottage
Srinivasa P.S. Rao
Kevin D. Read
Isabela Ribeiro
Lynn L. Silver
Jen Southern
Thomas Spangenberg
Shyam Sundar
Caitlin Taylor
Wes Van Voorhis
Nicholas J. White
Susan Wyllie
Paul G. Wyatt
Ian H. Gilbert
David Horn
Bree Aldridge
Richard K. Amewu
Clifton E. Barry
Frederick S. Buckner
Sarah Cook
Michael A.J. Ferguson
Nathalie Gobeau
Jennifer Herrmann
Paul Herrling
William Hope
Jennifer Keiser
Maria Jose Lafuente-Monasterio
Paul D. Leeson
Didier Leroy
Ujjini H. Manjunatha
James McCarthy
Timothy J. Miles
Valerie Mizrahi
Olena Moshynets
Jacquin Niles
John P. Overington
John Pottage
Srinivasa P.S. Rao
Kevin D. Read
Isabela Ribeiro
Lynn L. Silver
Jen Southern
Thomas Spangenberg
Shyam Sundar
Caitlin Taylor
Wes Van Voorhis
Nicholas J. White
Susan Wyllie
Paul G. Wyatt
Ian H. Gilbert
Other Contributor(s)
Lancaster Institute for the Contemporary Arts
ViiV Healthcare
Helmholtz-Institut für Pharmazeutische Forschung Saarland (HIPS)
GlaxoSmithKline plc, Spain
Institute of Molecular Biology and Genetics National Academy of Sciences of Ukraine
Banaras Hindu University, Institute of Medical Sciences
QIMR Berghofer Medical Research Institute
Universitat Basel
Swiss Tropical and Public Health Institute (Swiss TPH)
Massachusetts Institute of Technology
University of Liverpool
Merck KGaA
University of Ghana
National Institute of Allergy and Infectious Diseases
Tufts University School of Medicine
University of Washington, Seattle
Mahidol University
Helmholtz Centre for Infection Research (HZI)
University of Dundee
Novartis Institutes for BioMedical Research, Inc.
University of Glasgow
University of Cape Town
Paul Leeson Consulting Ltd.
LL Silver Consulting
Medicines for Malaria Venture
Drugs for Neglected Diseases Initiative
Medicines Discovery Catapult
Independent Consultant
ViiV Healthcare
Helmholtz-Institut für Pharmazeutische Forschung Saarland (HIPS)
GlaxoSmithKline plc, Spain
Institute of Molecular Biology and Genetics National Academy of Sciences of Ukraine
Banaras Hindu University, Institute of Medical Sciences
QIMR Berghofer Medical Research Institute
Universitat Basel
Swiss Tropical and Public Health Institute (Swiss TPH)
Massachusetts Institute of Technology
University of Liverpool
Merck KGaA
University of Ghana
National Institute of Allergy and Infectious Diseases
Tufts University School of Medicine
University of Washington, Seattle
Mahidol University
Helmholtz Centre for Infection Research (HZI)
University of Dundee
Novartis Institutes for BioMedical Research, Inc.
University of Glasgow
University of Cape Town
Paul Leeson Consulting Ltd.
LL Silver Consulting
Medicines for Malaria Venture
Drugs for Neglected Diseases Initiative
Medicines Discovery Catapult
Independent Consultant
Abstract
© 2019 American Chemical Society. In May 2019, the Wellcome Centre for Anti-Infectives Research (WCAIR) at the University of Dundee, UK, held an international conference with the aim of discussing some key questions around discovering new medicines for infectious diseases and a particular focus on diseases affecting Low and Middle Income Countries. There is an urgent need for new drugs to treat most infectious diseases. We were keen to see if there were lessons that we could learn across different disease areas and between the preclinical and clinical phases with the aim of exploring how we can improve and speed up the drug discovery, translational, and clinical development processes. We started with an introductory session on the current situation and then worked backward from clinical development to combination therapy, pharmacokinetic/pharmacodynamic (PK/PD) studies, drug discovery pathways, and new starting points and targets. This Viewpoint aims to capture some of the learnings.