Publication: Clinical profiles of thai patients with ocular myasthenia gravis in Siriraj Hospital
Issued Date
2011-09-01
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ISSN
01252208
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2-s2.0-80053091372
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Mahidol University
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SCOPUS
Bibliographic Citation
Journal of the Medical Association of Thailand. Vol.94, No.9 (2011), 1117-1121
Suggested Citation
Supinda Leeamornsiri, Niphon Chirapapaisan, Wanicha Chuenkongkaew Clinical profiles of thai patients with ocular myasthenia gravis in Siriraj Hospital. Journal of the Medical Association of Thailand. Vol.94, No.9 (2011), 1117-1121. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/12355
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Title
Clinical profiles of thai patients with ocular myasthenia gravis in Siriraj Hospital
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Abstract
Ninety-six patients with ocular myasthenia gravis (OMG) seen at Siriraj Hospital during 1994 to 2004 were retrospectively reviewed. There were 59 female (61.5%) and 37 (38.5%) male patients with mean ages of 39.5 and 33.8 years, respectively. Patients presented with initial symptoms of only ptosis in 46.9%, only diplopia in 13.5% and both ptosis and diplopia in 39.6%. However, diplopia alone is uncommon in childhood OMG. Fifteen percent developed systemic symptoms within two years of diagnosis. Thyroid function test was abnormal in 27.5% of investigated patients. Most abnormalities were hyperthyroidism. Thymoma associated with OMG is a rare condition. Most purely OMG patients can control the disease by pyridostigmine, prednisolone or immunosuppressive drugs.