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Synthesis of the Tetrahydropyran Fragment of Bistramide D

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dc.contributor.authorRoderick W. Batesen_US
dc.contributor.authorLu Lien_US
dc.contributor.authorKalpana Palanien_US
dc.contributor.authorWanida Phetsangen_US
dc.contributor.authorJoanna Kejun Lohen_US
dc.contributor.otherNanyang Technological Universityen_US
dc.contributor.otherMahidol Universityen_US
dc.date.accessioned2018-11-09T02:07:21Z
dc.date.available2018-11-09T02:07:21Z
dc.date.issued2014-01-01en_US
dc.description.abstractA synthesis of the tetrahydropyran (THP) moiety of bistramideD has been completed by using cross-metathesis and kinetically controlled intramolecular oxa-Michael addition to form the ring with excellent trans selectivity. The C9 methyl substituent was introduced by using an unsaturated sulfone building block, which can be most effectively prepared through a combination of diastereoselective allylation and alkene isomerisation. The effect of this methyl group on subsequent cross-metathesis reactions can be mitigated by careful choice of reaction conditions. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.en_US
dc.identifier.citationAsian Journal of Organic Chemistry. Vol.3, No.7 (2014), 792-796en_US
dc.identifier.doi10.1002/ajoc.201402052en_US
dc.identifier.issn21935807en_US
dc.identifier.issn21935807en_US
dc.identifier.other2-s2.0-84903777289en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/20.500.14594/33647
dc.rightsMahidol Universityen_US
dc.rights.holderSCOPUSen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84903777289&origin=inwarden_US
dc.subjectChemistryen_US
dc.titleSynthesis of the Tetrahydropyran Fragment of Bistramide Den_US
dc.typeArticleen_US
dspace.entity.typePublication
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84903777289&origin=inwarden_US

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