Publication: Toxic and mutagenic effects of formaldehyde in Salmonella typhimurium
Issued Date
1983-01-01
Resource Type
ISSN
01657992
Other identifier(s)
2-s2.0-0020656169
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Mahidol University
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SCOPUS
Bibliographic Citation
Mutation Research Letters. Vol.119, No.2 (1983), 89-93
Suggested Citation
Punya Temcharoen, William G. Thilly Toxic and mutagenic effects of formaldehyde in Salmonella typhimurium. Mutation Research Letters. Vol.119, No.2 (1983), 89-93. doi:10.1016/0165-7992(83)90115-X Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/30459
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Title
Toxic and mutagenic effects of formaldehyde in Salmonella typhimurium
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Abstract
Toxic and mutagenic activities of formaldehyde were studied in Salmonella typhimurium strain TM677, using forward mutation to 8-azaguanine (8-AG) resistance both in the absence and in the presence of Aroclor-induced rat-liver postmitochondrial supernatant (PMS). The results showed that formaldehyde was toxic and mutagenic to the bacteria in both systems, but toxicity and mutagenicity were reduced in the presence of PMS. The minimum concentration required to induce toxicity and mutagenicity was 0.17 mM in the absence of PMS and 0.33 mM in the presence of PMS. © 1983.