Publication: Hydrolysis and absorption of glucose polymers from rice compared with corn in chronic diarrhea of infancy
12
Issued Date
1990-01-01
Resource Type
ISSN
00223476
Other identifier(s)
2-s2.0-0025336035
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
The Journal of Pediatrics. Vol.116, No.6 (1990), 876-881
Suggested Citation
Daniel G. Sloven, Pipop Jirapinyo, Emanuel Lebenthal Hydrolysis and absorption of glucose polymers from rice compared with corn in chronic diarrhea of infancy. The Journal of Pediatrics. Vol.116, No.6 (1990), 876-881. doi:10.1016/S0022-3476(05)80643-2 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/16152
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Title
Hydrolysis and absorption of glucose polymers from rice compared with corn in chronic diarrhea of infancy
Author(s)
Abstract
Because rice remains the most available carbohydrate in developing countries, where chronic diarrhea is most prevalent, we compared the in vitro hydrolysis and clinical tolerance of rice glucose polymer with those of corn glucose polymer. Rice glucose polymer hydrolysis to d-glucose and short-chain polymers (polymers with two to four glucose units and those with five or more units) was similar to that for corn glucose polymers during incubation with saliva or duodenal aspirates. However, rice glucose polymers yielded more short-chain products than corn glucose polymers during incubation with pooled mucosal homogenates (p < 0.01). In vivo tolerance testing of 16 infants with chronic diarrhea confirmed that rice glucose polymers were well tolerated and, compared with corn glucose polymers, achieved a higher maximal increase of serum glucose concentration (36.6±7.3 vs 27.6±10.3 mg/dl; p < 0.02), a shorter time to peak serum glucose concentration (34.0±10.2 vs 52.5±25.7 minules; p < 0.02), and a greater area under the serum glucose response curve at 30 minutes (538±131 vs 1035±501 cm; p < 0.02). We conclude that rice glucose polymers are rapidly hydrolyzed in vitro and in vivo and are more rapidly absorbed than are corn glucose polymers in children with chronic diarrhea. © 1990 Mosby-year Book, Inc.