Publication: Detection of human papillomavirus in oral squamous cell carcinoma, leukoplakia and lichen planus in Thai patients
Issued Date
2008-01-01
Resource Type
ISSN
2476762X
15137368
15137368
Other identifier(s)
2-s2.0-66149112946
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Mahidol University
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SCOPUS
Bibliographic Citation
Asian Pacific Journal of Cancer Prevention. Vol.9, No.4 (2008), 771-775
Suggested Citation
Siribang on P Khovidhunkit, Waranun Buajeeb, Sirima Sanguansin, Sopee Poomsawat, Woranut Weerapradist Detection of human papillomavirus in oral squamous cell carcinoma, leukoplakia and lichen planus in Thai patients. Asian Pacific Journal of Cancer Prevention. Vol.9, No.4 (2008), 771-775. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/18992
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Title
Detection of human papillomavirus in oral squamous cell carcinoma, leukoplakia and lichen planus in Thai patients
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Abstract
Although tobacco, alcohol abuse and betel nut chewing habit are well recognized risk factors for oral squamous cell carcinoma (OSCC), there is evidence to indicate that human papillomavirus (HPV) may also play some inducing role. The purpose of this study was to investigate the presence of HPV in Thai patients with oral squamous cell carcinoma, leukoplakia and lichen planus using the polymerase chain reaction (PCR). Biopsies of oral squamous cell carcinoma, leukoplakia and lichen planus were obtained from 65 patients, 15 males and 50 females, aged between 30-88 years old. Extracted DNA was evaluated for HPV infections by PCR analysis using consensus primers specific for L1 region of HPV. Only one sample (1.54%) was positive, suggesting that HPV may not play an important role in this group of Thai patients.