Publication: Plasmodium vivax susceptibility to ferroquine
dc.contributor.author | M. L. Leimanis | en_US |
dc.contributor.author | A. Jaidee | en_US |
dc.contributor.author | K. Sriprawat | en_US |
dc.contributor.author | S. Kaewpongsri | en_US |
dc.contributor.author | R. Suwanarusk | en_US |
dc.contributor.author | M. Barends | en_US |
dc.contributor.author | A. P. Phyo | en_US |
dc.contributor.author | B. Russell | en_US |
dc.contributor.author | L. Renia | en_US |
dc.contributor.author | F. Nosten | en_US |
dc.contributor.other | Shoklo Malaria Research Unit | en_US |
dc.contributor.other | Agency for Science, Technology and Research, Singapore | en_US |
dc.contributor.other | Mahidol University | en_US |
dc.contributor.other | John Radcliffe Hospital | en_US |
dc.date.accessioned | 2018-09-24T09:29:41Z | |
dc.date.available | 2018-09-24T09:29:41Z | |
dc.date.issued | 2010-05-01 | en_US |
dc.description.abstract | The novel organometallic chloroquine analog ferroquine (SSR 97193) is effective against chloroquine-resistant Plasmodium falciparum. The ex vivo efficacy of ferroquine against Plasmodium vivax isolates was tested. Ferroquine has a potent ex vivo effect on P. vivax schizont maturation (median 50% inhibitory concentration, 15 nM; n = 42). No significant cross-sensitivity between ferroquine and other antimalarials was detected. This drug may be a suitable replacement for chloroquine in the treatment of drug-resistant P. vivax malaria. Copyright © 2010, American Society for Microbiology. All Rights Reserved. | en_US |
dc.identifier.citation | Antimicrobial Agents and Chemotherapy. Vol.54, No.5 (2010), 2228-2230 | en_US |
dc.identifier.doi | 10.1128/AAC.01572-09 | en_US |
dc.identifier.issn | 10986596 | en_US |
dc.identifier.issn | 00664804 | en_US |
dc.identifier.other | 2-s2.0-77951228214 | en_US |
dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/20.500.14594/29696 | |
dc.rights | Mahidol University | en_US |
dc.rights.holder | SCOPUS | en_US |
dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77951228214&origin=inward | en_US |
dc.subject | Medicine | en_US |
dc.subject | Pharmacology, Toxicology and Pharmaceutics | en_US |
dc.title | Plasmodium vivax susceptibility to ferroquine | en_US |
dc.type | Article | en_US |
dspace.entity.type | Publication | |
mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77951228214&origin=inward | en_US |