Publication: Persistent perineal sinus: Incidence, pathogenesis, risk factors, and management
Issued Date
2009-03-01
Resource Type
ISSN
14362813
09411291
09411291
Other identifier(s)
2-s2.0-62449256659
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Surgery Today. Vol.39, No.3 (2009), 189-193
Suggested Citation
Varut Lohsiriwat Persistent perineal sinus: Incidence, pathogenesis, risk factors, and management. Surgery Today. Vol.39, No.3 (2009), 189-193. doi:10.1007/s00595-008-3846-z Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/28159
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Title
Persistent perineal sinus: Incidence, pathogenesis, risk factors, and management
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Abstract
This review discusses the incidence, pathogenesis, risk factors, diagnosis, and therapeutic options for persistent perineal sinus (PPS), defined as a perineal wound that remains unhealed more than 6 months after surgery. The incidence of PPS after surgery for inflammatory bowel disease (IBD) ranges from 3% to 70% and after abdominoperineal resection (APR) for low rectal cancer, it can be up to 30%. These unhealed wounds are frequently related to perioperative pelvic or perineal sepsis. Crohn's disease (CD) and neoadjuvant radiation therapy are also important risk factors. The management of PPS is based on an understanding of pathogenesis and clinical grounds. The advantages and disadvantages of the current therapeutic approaches, including the topical administration of various drugs, vacuum-assisted closure, and perineal reconstruction with a muscle flap or a myocutaneous flap are also discussed. © 2009 Springer.