Publication: Surveillance of transmitted HIV drug resistance in antiretroviral-naive patients aged less than 25 years, in Bangkok, Thailand
Issued Date
2014-01-01
Resource Type
ISSN
23259582
23259574
23259574
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2-s2.0-84893147061
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Mahidol University
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SCOPUS
Bibliographic Citation
Journal of the International Association of Providers of AIDS Care. Vol.13, No.1 (2014), 12-14
Suggested Citation
Somnuek Sungkanuparph, Ekawat Pasomsub, Wasun Chantratita Surveillance of transmitted HIV drug resistance in antiretroviral-naive patients aged less than 25 years, in Bangkok, Thailand. Journal of the International Association of Providers of AIDS Care. Vol.13, No.1 (2014), 12-14. doi:10.1177/2325957413488200 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/34039
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Title
Surveillance of transmitted HIV drug resistance in antiretroviral-naive patients aged less than 25 years, in Bangkok, Thailand
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Abstract
Emergence of transmitted HIV drug resistance (TDR) is a concern after global scale-up of antiretroviral therapy (ART). World Health Organization had developed threshold survey method for surveillance of TDR in resource-limited countries. ART in Thailand has been scaling up for >10 years. To evaluate the current TDR in Thailand, a cross-sectional study was conducted among antiretroviral-naive HIV-infected patients aged <25 years who newly visited infectious disease clinic in a university hospital, in 2011. HIV genotypic-resistance test was performed. World Health Organization 2009 surveillance drug-resistance mutations were used to define TDR. Of 50 patients, the prevalence of TDR was 4%. Of 2 patients with TDR, 1 had K103N and the other had Y181C mutations. Transmitted HIV drug resistance is emerging in Thailand after a decade of rapid scale-up of ART. Interventions to prevent TDR at the population level are essentially needed in Thailand. Surveillance for TDR in Thailand has to be regularly performed. © The Author(s) 2013.