Publication:
Antimycobacterial anthraquinone-chromanone compound and diketopiperazine alkaloid from the fungus Chaetomium globosum KMITL-N0802

Issued Date

2002-09-01

Resource Type

Article

ISSN

00320943

DOI

10.1055/s-2002-34415

Other identifier(s)

2-s2.0-0036749129

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Planta Medica. Vol.68, No.9 (2002), 834-836

Suggested Citation

Somdej Kanokmedhakul, Kwanjai Kanokmedhakul, Nutchanat Phonkerd, Kasem Soytong, Palangpon Kongsaeree, Apichart Suksamrarn Antimycobacterial anthraquinone-chromanone compound and diketopiperazine alkaloid from the fungus Chaetomium globosum KMITL-N0802. Planta Medica. Vol.68, No.9 (2002), 834-836. doi:10.1055/s-2002-34415 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/19974

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Title

Antimycobacterial anthraquinone-chromanone compound and diketopiperazine alkaloid from the fungus Chaetomium globosum KMITL-N0802

Author(s)

Somdej Kanokmedhakul
 Kwanjai Kanokmedhakul
 Nutchanat Phonkerd
 Kasem Soytong
 Palangpon Kongsaeree
 Apichart Suksamrarn

Other Contributor(s)

Khon Kaen University
 King Mongkut's Institute of Technology Ladkrabang
 Mahidol University
 Ramkhamhaeng University

Abstract

Investigation of the fungus Chaetomium globosum KMITL-N0802 led to the isolation of a novel anthraquinone-chromanone compound named chaetomanone along with seven known compounds, ergosterol, ergosteryl palmitate, chrysophanol, chaetoglobosin C, alternariol monomethyl ether, echinuline and isochaetoglobosin D. These compounds were characterized by spectroscopic methods. Chaetomanone and echinulin exhibited activity towards Mycobacterium tuberculosis.

Keyword(s)

Agricultural and Biological Sciences
 Chemistry
 Pharmacology, Toxicology and Pharmaceutics

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/19974

Collections

Scopus 2001-2005