Publication: Antimutagenic activity of Sesbania javanica Miq. flower DMSO extract and its major flavonoid glycoside
Issued Date
2005-11-01
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ISSN
01251562
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2-s2.0-33645025935
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Mahidol University
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SCOPUS
Bibliographic Citation
Southeast Asian Journal of Tropical Medicine and Public Health. Vol.36, No.6 (2005), 1543-1551
Suggested Citation
Surapon Tangvarasittichai, Nimit Sriprang, Talabporn Harnroongroj, Supranee Changbumrung Antimutagenic activity of Sesbania javanica Miq. flower DMSO extract and its major flavonoid glycoside. Southeast Asian Journal of Tropical Medicine and Public Health. Vol.36, No.6 (2005), 1543-1551. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/16749
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Title
Antimutagenic activity of Sesbania javanica Miq. flower DMSO extract and its major flavonoid glycoside
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Abstract
The antimutagenic activity of Sesbania javanica Miq. or Sano, an edible vegetable flower DMSO extract against aflatoxin B1 (AFB1) benzo (a) pyrene [B(a)P], was evaluated by means of the Ames' test. The Sesbania javanica Miq. flower DMSO extract showed a strong inhibitory effect against AFB 1 and B(a)P mutagens. A search to isolate the major flavonoid in Sesbania javanica Miq. flower extract found the flavonol glycoside, Quercetin 3-2G-rhamnosylrutinoside, which was confirmed by its physicochemical properties as a major constituent of the flower. Quercetin 3-2 G-rhamnosylrutinoside (207 pg/plate) also showed a strong inhibitory effect against AFB1 and B(a)P with a more than 70% inhibition rate.