Publication: Varicella-zoster meningitis with a late-onset of skin eruption
Issued Date
2015-02-17
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ISSN
1757790X
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2-s2.0-84923385381
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Mahidol University
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SCOPUS
Bibliographic Citation
BMJ Case Reports. Vol.2015, (2015)
Suggested Citation
Anawin Sanguankeo, Sikarin Upala, Suthanya Sornprom, Natanong Thamcharoen Varicella-zoster meningitis with a late-onset of skin eruption. BMJ Case Reports. Vol.2015, (2015). doi:10.1136/bcr-2014-208056 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/36509
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Title
Varicella-zoster meningitis with a late-onset of skin eruption
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Abstract
Copyright 2015 BMJ Publishing Group. All rights reserved. Viral meningitis caused by varicella-zoster virus (VZV) is an uncommon neurological complication of herpes zoster. It may occur before or after the onset of the vesicular rash along the dermatomal distribution, which is the classic presentation of herpes zoster. We describe a case of a 51-year-old immunocompetent Caucasian man who presented with neck and severe right-sided facial pain. Eight days later, he had photophobia and papular rash on his forehead. Cerebrospinal fluid (CSF) examination confirmed aseptic meningitis and CSF PCR detected the presence of VZV DNA. Neurological complications of VZV infection, such as aseptic meningitis, may be difficult to diagnose and can cause delay in treatment, especially in cases with late onset of dermatological manifestations of herpes zoster. Definite diagnosis requires evidence of acute VZV infection in blood or cerebrospinal fluid.