Publication:
Dynamical Modelling of Bone Formation and Resorption under Impulsive Estrogen Supplement: Effects of Parathyroid Hormone and Prolactin

1

Issued Date

2021-01-01

Resource Type

Article

ISSN

16870425
01611712

DOI

10.1155/2021/5435876

Other identifier(s)

2-s2.0-85122529475

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

International Journal of Mathematics and Mathematical Sciences. Vol.2021, (2021)

Suggested Citation

Supassorn Aekthong, Chontita Rattanakul Dynamical Modelling of Bone Formation and Resorption under Impulsive Estrogen Supplement: Effects of Parathyroid Hormone and Prolactin. International Journal of Mathematics and Mathematical Sciences. Vol.2021, (2021). doi:10.1155/2021/5435876 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/77384

Research Projects

Organizational Units

Authors

Journal Issue

Thesis

Title

Dynamical Modelling of Bone Formation and Resorption under Impulsive Estrogen Supplement: Effects of Parathyroid Hormone and Prolactin

Author(s)

Supassorn Aekthong
 Chontita Rattanakul

Other Contributor(s)

Mahidol University
 Centre of Excellence in Mathematics

Abstract

Osteoporosis, a bone metabolic disease, is one of the major diseases occurring in aging population especially in postmenopausal women. A system of impulsive differential equations is developed in this paper in order to investigate the effects of parathyroid hormone and prolactin on bone-forming cells, namely, osteoblasts, and bone-resorbing cells, namely, osteoclasts, under the impulsive estrogen supplement. The theoretical analysis of the developed model is carried out so that we obtain the conditions on the system parameters in which the stability and permanence of the model can occur. Computer simulations are also provided to illustrate the theoretical predictions.

Keyword(s)

Mathematics

Availability

URI

https://repository.li.mahidol.ac.th/handle/123456789/77384

Collections

Scopus 2021