Publication: Albendazole treatment for Giardia intestinalis infections in school children
Issued Date
1999-03-01
Resource Type
ISSN
01251562
Other identifier(s)
2-s2.0-0033084705
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Mahidol University
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SCOPUS
Bibliographic Citation
Southeast Asian Journal of Tropical Medicine and Public Health. Vol.30, No.1 (1999), 78-83
Suggested Citation
Krisana Pengsaa, Chukiet Sirivichayakul, Chanathep Pojjaroen-anant, Sawat Nimnual, Pataraporn Wisetsing Albendazole treatment for Giardia intestinalis infections in school children. Southeast Asian Journal of Tropical Medicine and Public Health. Vol.30, No.1 (1999), 78-83. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/25676
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Title
Albendazole treatment for Giardia intestinalis infections in school children
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Abstract
A randomized controlled trial, 113 school children with Giardia intestinalis infection were treated with albendazole or tinidazole. Albendazole 400 mg once a day x 3 days and tinidazole 50 mg/kg single dose were given orally to 62 and 51 children, respectively. Parasitological cure was documented when there were ≥ 2 times negative stool examination for G. intestinalis at 1-2 weeks after therapy. Thirty-one of 62 (50%) children treated with albendazole and 49 of 51 (96.1 %) children treated with tinidazole had parasitological cure (p < 0.001). No major side effects were observed except one case in tinidazole group had severe headache for 30 hours. Albendazole appears to be safe and produced a moderate cure rate for G. intestinalis infection when a 3 day anthelmintic regimen is given.