Publication: Three novel biphenanthrene derivatives and a new phenylpropanoid ester from aerides multiflora and their α‐glucosidase inhibitory activity
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Issued Date
2021-02-01
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ISSN
22237747
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2-s2.0-85101101437
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Mahidol University
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SCOPUS
Bibliographic Citation
Plants. Vol.10, No.2 (2021), 1-14
Suggested Citation
May Thazin Thant, Boonchoo Sritularak, Nutputsorn Chatsumpun, Wanwimon Mekboonsonglarp, Yanyong Punpreuk, Kittisak Likhitwitayawuid Three novel biphenanthrene derivatives and a new phenylpropanoid ester from aerides multiflora and their α‐glucosidase inhibitory activity. Plants. Vol.10, No.2 (2021), 1-14. doi:10.3390/plants10020385 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/75733
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Title
Three novel biphenanthrene derivatives and a new phenylpropanoid ester from aerides multiflora and their α‐glucosidase inhibitory activity
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Abstract
A phytochemical investigation on the whole plants of Aerides multiflora revealed the presence of three new biphenanthrene derivatives named aerimultins A–C (1–3) and a new natural phenylpropanoid ester dihydrosinapyl dihydroferulate (4), together with six known compounds (5–10). The structures of the new compounds were elucidated by analysis of their spectroscopic data. All of the isolates were evaluated for their α‐glucosidase inhibitory activity. Aerimultin C (3) showed the most potent activity. The other compounds, except for compound 4, also exhibited stronger activity than the positive control acarbose. Compound 3 showed non‐competitive inhibition of the enzyme as determined from a Lineweaver–Burk plot. This study is the first phytochemical and biological investigation of A. multiflora.