Publication: Antibacterial, antifungal, and antimycobacterial activity of Ilex aquifolium leaves
5
Issued Date
2009-08-01
Resource Type
ISSN
17445116
13880209
13880209
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2-s2.0-77149121819
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Mahidol University
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SCOPUS
Bibliographic Citation
Pharmaceutical Biology. Vol.47, No.8 (2009), 697-700
Suggested Citation
Nurgün Erdemoglu, Gökalp Iscan, Bilge Sener, Prasit Palittapongarnpim Antibacterial, antifungal, and antimycobacterial activity of Ilex aquifolium leaves. Pharmaceutical Biology. Vol.47, No.8 (2009), 697-700. doi:10.1080/13880200902930431 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/27174
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Title
Antibacterial, antifungal, and antimycobacterial activity of Ilex aquifolium leaves
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Abstract
The objective of this study was to examine antibacterial, antifungal, and antimycobacterial properties of Ilex aquifolium L. (Aquifoliaceae) growing in Turkey. The ethanol, ethyl acetate, chloroform, and n-hexane extracts prepared from the leaves of I. aquifolium were tested against Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Enterobacter aerogenes, Proteus vulgaris, Salmonella typhimurium, and Candida albicans for antibacterial and antifungal evaluation using the microdilution broth susceptibility assay. In addition, antimycobacterial activity of the crude extracts of I. aquifolium was evaluated by microplate Alamar blue assay. The results showed that the extracts tested, except n-hexane, possessed moderate antibacterial and antifungal activity varying from 62.5 to 250μg/mL. On the other hand, the ethanol extract of the leaves exhibited a minimum inhibitory concentration value (MIC) against Mycobacterium tuberculosis H37Ra strain of 200 μg/mL. © 2009 Informa UK Ltd.