Publication:
Synthesis of D-FucNAc-D-ManNAcA Disaccharides Based on the Capsular Polysaccharides Staphylococcus aureus Type 5 and 8

Issued Date

2019-01-04

Resource Type

Article

ISSN

15206904
00223263

DOI

10.1021/acs.joc.8b02612

Other identifier(s)

2-s2.0-85059587313

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Journal of Organic Chemistry. Vol.84, No.1 (2019), 216-227

Suggested Citation

Satsawat Visansirikul, Stephen A. Kolodziej, Alexei V. Demchenko Synthesis of D-FucNAc-D-ManNAcA Disaccharides Based on the Capsular Polysaccharides Staphylococcus aureus Type 5 and 8. Journal of Organic Chemistry. Vol.84, No.1 (2019), 216-227. doi:10.1021/acs.joc.8b02612 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/50580

Research Projects

Organizational Units

Authors

Journal Issue

Thesis

Title

Synthesis of D-FucNAc-D-ManNAcA Disaccharides Based on the Capsular Polysaccharides Staphylococcus aureus Type 5 and 8

Author(s)

Satsawat Visansirikul
 Stephen A. Kolodziej
 Alexei V. Demchenko

Other Contributor(s)

University of Missouri-St. Louis
 Mahidol University
 Bioprocess RandD

Abstract

© 2018 American Chemical Society. To gain a better understanding of the conjugation chemistry taking place at the interface of the capsular polysaccharide repeating units, described herein is the synthesis of two disaccharides. These disaccharides correspond to the connection point of the repeating units of capsular polysaccharide S. aureus serotype 5 (CP5) and serotype 8 (CP8). As in our previous syntheses of trisaccharide repeating units, the potential propagation positions are blocked with methyl groups.

Keyword(s)

Chemistry

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/50580

Collections

Scopus 2019