Publication: Reduction of cytotoxicity of natural rubber latex film by coating with PMMA-chitosan nanoparticles
Issued Date
2013-01-01
Resource Type
ISSN
01448617
Other identifier(s)
2-s2.0-84878008170
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Carbohydrate Polymers. Vol.97, No.1 (2013), 52-58
Suggested Citation
Nuttakun Kanjanathaworn, Duangporn Polpanich, Kulachart Jangpatarapongsa, Pramuan Tangboriboonrat Reduction of cytotoxicity of natural rubber latex film by coating with PMMA-chitosan nanoparticles. Carbohydrate Polymers. Vol.97, No.1 (2013), 52-58. doi:10.1016/j.carbpol.2012.12.078 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/31566
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Reduction of cytotoxicity of natural rubber latex film by coating with PMMA-chitosan nanoparticles
Other Contributor(s)
Abstract
Poly(methyl methacrylate) (PMMA) latex stabilized by chitosan (CS) oligomer was synthesized via the miniemulsion polymerization. By using 1% CS solution (in 0.1 M acetic acid), the spherical PMMA-CS particles with an average size of 380 nm were obtained. The positive zeta potentials at pH 2-7 confirmed the presence of CS as the outermost layer of the latex particles. Therefore, these particles directly interacted with the indigenous non-rubbers at the surface of sulphur prevulcanized natural rubber (SPNR) film. The deposition of PMMA-CS particles caused an increase in surface roughness of the coated SPNR film as a function of latex concentration and immersion time. The simple coating of the rubber substrate with PMMA-CS particles effectively reduced the in vitro cytotoxicity on L-929 cells. This study would be, therefore, helpful for development of latex gloves designed for hypersensitive users. © 2013 Elsevier Ltd. All rights reserved.