Publication: Effectiveness of intrauterine anesthesia for pain relief during fractional curettage
2
Issued Date
2005-01-01
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ISSN
00297844
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2-s2.0-23944453378
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Mahidol University
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SCOPUS
Bibliographic Citation
Obstetrics and Gynecology. Vol.106, No.3 (2005), 533-539
Suggested Citation
Manee Rattanachaiyanont, Pichai Leerasiri, Suchada Indhavivadhana Effectiveness of intrauterine anesthesia for pain relief during fractional curettage. Obstetrics and Gynecology. Vol.106, No.3 (2005), 533-539. doi:10.1097/01.AOG.0000172424.09992.3e Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/17100
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Title
Effectiveness of intrauterine anesthesia for pain relief during fractional curettage
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Abstract
Objective: To study the effectiveness of intrauterine anesthesia for pain relief during fractional curettage. Methods: A double-blinded, randomized, placebo-controlled trial was conducted in 66 patients with abnormal uterine bleeding undergoing fractional curettage under paracervical block, using 10-mL 1% lidocaine plus intrauterine 5-mL 2% lidocaine (n = 33) or saline (n = 33). The primary outcome was the maximum pain score measured with a 10-cm visual analog scale. Other outcomes measured included pain profile, number of patients with pain score more than 4, each patient's global satisfaction index, adverse events, and serum lidocaine profile. Results: The 2 groups were comparable in age, body mass index, education, socioeconomic status, menopausal status, and parity. Compared with the saline group, the lidocaine group had a significantly lower median value for the maximum pain score (2.3 versus 4.7, P = .022) and fewer patients with a pain score more than 4 (33.3% versus 60.6%, P = .026). The pain scores were lower at the endocervical curettage and the uterine curettage steps. There was no difference between the 2 groups in other outcomes. The number needed to treat to prevent a case with a pain score more than 4 was 3.7 (95% confidence interval 2.4-38.5). Conclusion: The addition of intrauterine anesthesia to paracervical block can further reduce pain during fractional curettage without increasing adverse effects. © 2005 by The American College of Obstetricians and Gynecologists. Published by Lippincott Williams & Wilkins.