Publication:
Antihypertensive effect of BS 100-141, a new central acting antihypertensive agent

Issued Date

1980-01-01

Resource Type

Article

ISSN

10976744
00028703

DOI

10.1016/0002-8703(80)90314-2

Other identifier(s)

2-s2.0-0018875707

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

American Heart Journal. Vol.99, No.1 (1980), 58-63

Suggested Citation

Somchart Lochaya, Vipa Thongmitr, Orawan Suvachittanont Antihypertensive effect of BS 100-141, a new central acting antihypertensive agent. American Heart Journal. Vol.99, No.1 (1980), 58-63. doi:10.1016/0002-8703(80)90314-2 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/11166

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Title

Antihypertensive effect of BS 100-141, a new central acting antihypertensive agent

Author(s)

Somchart Lochaya
 Vipa Thongmitr
 Orawan Suvachittanont

Other Contributor(s)

Mahidol University

Abstract

A double-blind comparison between BS 100-141 and placebo in 36 hypertensive patients of Thai or Thai-Chinese origin revealed that the preparation lowers the elevated blood pressure within the first week of treatment in most patients. The drug was relatively well tolerated and caused mild side effects only. After a sudden discontinuation of the drug, the blood pressure in four of the 19 patients increased within a few days to pretreatment values or slightly above. The occurrence of rebound hypertension cannot be excluded. Interruption of treatment, therefore, should be made gradually. © 1980.

Keyword(s)

Medicine

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URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/11166

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Scopus 1969-1990