Publication: Effect of antiretroviral therapy on plasma concentrations of chloroquine and desethyl-chloroquine
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2018-10-30
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15376591
10584838
10584838
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2-s2.0-85055631898
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Mahidol University
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SCOPUS
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Clinical Infectious Diseases. Vol.67, No.10 (2018), 1617-1620
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Matthew M. Ippolito, Jeffrey M. Jacobson, Michael M. Lederman, Markus Winterberg, Joel Tarning, Theresa A. Shapiro, Charles Flexner Effect of antiretroviral therapy on plasma concentrations of chloroquine and desethyl-chloroquine. Clinical Infectious Diseases. Vol.67, No.10 (2018), 1617-1620. doi:10.1093/cid/ciy405 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/46240
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Effect of antiretroviral therapy on plasma concentrations of chloroquine and desethyl-chloroquine
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© The Author(s) 2018. Published by Oxford University Press for the Infectious Diseases Society of America. The effect of antiretroviral therapy (ART) on chloroquine and desethyl-chloroquine plasma concentrations was evaluated in clinical trial participants. Concentrations did not differ among participants receiving protease inhibitor-based ART (n = 9), efavirenz-based ART (n = 15), or other ART (n = 8) and those not receiving ART (n = 31). Efavirenz seemed to inhibit chloroquine desethylation.