Publication: Effect of antiretroviral therapy on plasma concentrations of chloroquine and desethyl-chloroquine
Issued Date
2018-10-30
Resource Type
ISSN
15376591
10584838
10584838
Other identifier(s)
2-s2.0-85055631898
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Clinical Infectious Diseases. Vol.67, No.10 (2018), 1617-1620
Suggested Citation
Matthew M. Ippolito, Jeffrey M. Jacobson, Michael M. Lederman, Markus Winterberg, Joel Tarning, Theresa A. Shapiro, Charles Flexner Effect of antiretroviral therapy on plasma concentrations of chloroquine and desethyl-chloroquine. Clinical Infectious Diseases. Vol.67, No.10 (2018), 1617-1620. doi:10.1093/cid/ciy405 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/46240
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Effect of antiretroviral therapy on plasma concentrations of chloroquine and desethyl-chloroquine
Abstract
© The Author(s) 2018. Published by Oxford University Press for the Infectious Diseases Society of America. The effect of antiretroviral therapy (ART) on chloroquine and desethyl-chloroquine plasma concentrations was evaluated in clinical trial participants. Concentrations did not differ among participants receiving protease inhibitor-based ART (n = 9), efavirenz-based ART (n = 15), or other ART (n = 8) and those not receiving ART (n = 31). Efavirenz seemed to inhibit chloroquine desethylation.