Publication:
Nanotechnology applications of flavonoids for viral diseases

dc.contributor.authorKhoshnur Jannaten_US
dc.contributor.authorAlok K. Paulen_US
dc.contributor.authorTohmina A. Bondhonen_US
dc.contributor.authorAnamul Hasanen_US
dc.contributor.authorMuhammad Nawazen_US
dc.contributor.authorRownak Jahanen_US
dc.contributor.authorTooba Mahbooben_US
dc.contributor.authorVeeranoot Nissapatornen_US
dc.contributor.authorPolrat Wilairatanaen_US
dc.contributor.authorMaria de Lourdes Pereiraen_US
dc.contributor.authorMohammed Rahmatullahen_US
dc.contributor.otherFaculty of Tropical Medicine, Mahidol Universityen_US
dc.contributor.otherImam Abdulrahman Bin Faisal universityen_US
dc.contributor.otherWalailak Universityen_US
dc.contributor.otherUniversity of Tasmaniaen_US
dc.contributor.otherCICECO – Instituto de Materiais de Aveiroen_US
dc.contributor.otherUniversity of Development Alternativeen_US
dc.date.accessioned2022-08-04T11:19:47Z
dc.date.available2022-08-04T11:19:47Z
dc.date.issued2021-11-01en_US
dc.description.abstractRecent years have witnessed the emergence of several viral diseases, including various zoonotic diseases such as the current pandemic caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Other viruses, which possess pandemic-causing potential include avian flu, Ebola, dengue, Zika, and Nipah virus, as well as the re-emergence of SARS (Severe Acute Respiratory Syndrome) and MERS (Middle East Respiratory Syndrome) coronaviruses. Notably, effective drugs or vaccines against these viruses are still to be discovered. All the newly approved vaccines against the SARS-CoV-2-induced disease COVID-19 possess real-time possibility of becoming obsolete because of the development of ‘variants of concern’. Flavonoids are being increasingly recognized as prophylactic and therapeutic agents against emerging and old viral diseases. Around 10,000 natural flavonoid compounds have been identified, being phytochemicals, all plant-based. Flavonoids have been reported to have lesser side effects than conventional anti-viral agents and are effective against more viral diseases than currently used anti-virals. Despite their abundance in plants, which are a part of human diet, flavonoids have the problem of low bioavailability. Various attempts are in progress to increase the bioavailability of flavonoids, one of the promising fields being nanotechnology. This review is a narrative of some anti-viral dietary flavonoids, their bioavailability, and various means with an emphasis on the nanotechnology system(s) being experimented with to deliver anti-viral flavonoids, whose systems show potential in the efficient delivery of flavonoids, resulting in increased bioavailability.en_US
dc.identifier.citationPharmaceutics. Vol.13, No.11 (2021)en_US
dc.identifier.doi10.3390/pharmaceutics13111895en_US
dc.identifier.issn19994923en_US
dc.identifier.other2-s2.0-85119600147en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/20.500.14594/78938
dc.rightsMahidol Universityen_US
dc.rights.holderSCOPUSen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85119600147&origin=inwarden_US
dc.subjectPharmacology, Toxicology and Pharmaceuticsen_US
dc.titleNanotechnology applications of flavonoids for viral diseasesen_US
dc.typeReviewen_US
dspace.entity.typePublication
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85119600147&origin=inwarden_US

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