Publication: Ophiobolins from the Mangrove Fungus Aspergillus ustus
| dc.contributor.author | Tonghan Zhu | en_US |
| dc.contributor.author | Zhenyu Lu | en_US |
| dc.contributor.author | Jie Fan | en_US |
| dc.contributor.author | Liping Wang | en_US |
| dc.contributor.author | Guoliang Zhu | en_US |
| dc.contributor.author | Yi Wang | en_US |
| dc.contributor.author | Xia Li | en_US |
| dc.contributor.author | Kui Hong | en_US |
| dc.contributor.author | Pawinee Piyachaturawat | en_US |
| dc.contributor.author | Arthit Chairoungdua | en_US |
| dc.contributor.author | Weiming Zhu | en_US |
| dc.contributor.other | Shandong University, Weihai | en_US |
| dc.contributor.other | Wuhan University | en_US |
| dc.contributor.other | Ocean University of China | en_US |
| dc.contributor.other | Chinese Academy of Sciences | en_US |
| dc.contributor.other | Mahidol University | en_US |
| dc.date.accessioned | 2019-08-23T10:38:09Z | |
| dc.date.available | 2019-08-23T10:38:09Z | |
| dc.date.issued | 2018-01-26 | en_US |
| dc.description.abstract | © 2017 The American Chemical Society and American Society of Pharmacognosy. Seven new ophiobolins (1-5, 12, and 14) along with the 11 known analogues (6-11, 13, 15-18) were isolated from the ethyl acetate extracts of the liquid and solid cultures of the mangrove fungus Aspergillus ustus 094102. The structures including the absolute configurations of the seven new compounds were elucidated by spectroscopic analysis, chemical methods, and quantum ECD calculations. Compounds 4-8 and 11-15 showed cytotoxicities against the G3K, MCF-7, MD-MBA-231, MCF/Adr, A549, and HL-60 human cancer cell lines with the IC 50 values ranging from 0.6 to 9.5 μM. | en_US |
| dc.identifier.citation | Journal of Natural Products. Vol.81, No.1 (2018), 2-9 | en_US |
| dc.identifier.doi | 10.1021/acs.jnatprod.7b00335 | en_US |
| dc.identifier.issn | 15206025 | en_US |
| dc.identifier.issn | 01633864 | en_US |
| dc.identifier.other | 2-s2.0-85041213491 | en_US |
| dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/20.500.14594/45264 | |
| dc.rights | Mahidol University | en_US |
| dc.rights.holder | SCOPUS | en_US |
| dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85041213491&origin=inward | en_US |
| dc.subject | Biochemistry, Genetics and Molecular Biology | en_US |
| dc.subject | Chemistry | en_US |
| dc.subject | Medicine | en_US |
| dc.subject | Pharmacology, Toxicology and Pharmaceutics | en_US |
| dc.title | Ophiobolins from the Mangrove Fungus Aspergillus ustus | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85041213491&origin=inward | en_US |