Publication: The antimalarial ferroquine: From bench to clinic
| dc.contributor.author | C. Biot | en_US |
| dc.contributor.author | F. Nosten | en_US |
| dc.contributor.author | L. Fraisse | en_US |
| dc.contributor.author | D. Ter-Minassian | en_US |
| dc.contributor.author | J. Khalife | en_US |
| dc.contributor.author | D. Dive | en_US |
| dc.contributor.other | University of Lille | en_US |
| dc.contributor.other | Shoklo Malaria Research Unit | en_US |
| dc.contributor.other | Mahidol University | en_US |
| dc.contributor.other | Nuffield Department of Clinical Medicine | en_US |
| dc.contributor.other | Sanofi S.A. | en_US |
| dc.contributor.other | Centre d'Infection et d'Immunite de Lille | en_US |
| dc.date.accessioned | 2018-05-03T07:58:10Z | |
| dc.date.available | 2018-05-03T07:58:10Z | |
| dc.date.issued | 2011-01-01 | en_US |
| dc.description.abstract | Ferroquine (FQ, SSR97193) is currently the most advanced organometallic drug candidate and about to complete phase II clinical trials as a treatment for uncomplicated malaria. This ferrocene-containing compound is active against both chloroquine-susceptible and chloroquine-resistant Plasmodium falciparum and P. vivax strains and/or isolates. This article focuses on the discovery of FQ, its antimalarial activity, the hypothesis of its mode of action, the current absence of resistance in vitro and recent clinical trials. | en_US |
| dc.identifier.citation | Parasite. Vol.18, No.3 (2011), 207-214 | en_US |
| dc.identifier.doi | 10.1051/parasite/2011183207 | en_US |
| dc.identifier.issn | 17761042 | en_US |
| dc.identifier.issn | 1252607X | en_US |
| dc.identifier.other | 2-s2.0-84855268494 | en_US |
| dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/20.500.14594/11390 | |
| dc.rights | Mahidol University | en_US |
| dc.rights.holder | SCOPUS | en_US |
| dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84855268494&origin=inward | en_US |
| dc.subject | Agricultural and Biological Sciences | en_US |
| dc.subject | Immunology and Microbiology | en_US |
| dc.title | The antimalarial ferroquine: From bench to clinic | en_US |
| dc.type | Review | en_US |
| dspace.entity.type | Publication | |
| mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84855268494&origin=inward | en_US |